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In some cancers, such as leukemias, malignant cells have markedly aberrant patterns of DNA methylation or histone modification.
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In preeclampsia, endothelium-dependent function is markedly aberrant.
Dubuc, A. M. et al. Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma.
When examining inheritance patterns in families occasionally aberrant patterns are observed.
One caveat, though, is that L-428 and L-1236 have markedly aberrant karyotypes.
These cells also showed aberrant patterns of chromosome condensation.
Certain types of histone modifications are associated with aberrant patterns of DNA methylation in cancer.
Mutation analysis of the entire Fas gene revealed no aberrant patterns in both cell lines.
In cancer cells, aberrant patterns of DNA methylation are frequently observed.
Such an aberrant pattern might depend on a lower pelvic incidence.
Moreover, this aberrant pattern can be included in the identification scheme.
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