The phrase "marked uptick" is correct and usable in written English.
It can be used to describe a noticeable increase in a particular metric or trend.
Example: "There has been a marked uptick in sales since the new marketing campaign was launched."
Alternatives: "significant increase" or "notable rise."
Currently, more than 6-in-10 (62%) Hispanics say they approve of the job Obama is doing as President a marked uptick from October 2014 when fewer than half (46%) of Hispanics expressed approval".
"We've had a marked uptick in business," he said.
In possibly related news, Quinnipiac polling in Virginia, Wisconsin and Colorado showed a marked uptick in confidence about the direction of the economy.
From Botox for frown lines and crow's feet to collagen, a bovine-based wrinkle filler for the lines around the mouth, lunchtime cosmetic rejuvenation has been surging, with a marked uptick since Sept. 11.
There is a marked uptick that I missed in 2013, but that ceased in the spring of 2014 and has turned down, more markedly admittedly in manufacturing than services.
"Indeed, it is this marked uptick in piracy and armed robbery at sea and the need to deter other individuals from undertaking this kind of conduct," Judge Preska said, that "makes the higher sentence absolutely necessary".
The figure marked an uptick from the group's estimate for the year prior, which stood at 79 per 100,000.
The tiny gun she had inked below her armpit marked an uptick in the number of asks for similar tats.
October 2018 marked an uptick in white nationalist violence in America: Proud Boys assaulted people in New York City; a man killed two people in a grocery store in Kentucky while telling a bystander that "whites don't shoot whites;" a man mailed pipe bombs to prominent democrats, journalists, and George Soros; a shooter murdered 11 people in a Pittsburgh synagogue.
This, of course, marked a sudden uptick in our cookie consumption.
There the issue rested until after the end of the Cold War, which marked the latest uptick in using civilians as a significant part of deployed armed forces.
