Sentence examples for marked synergistic effect from inspiring English sources
To improve sertraline efficiency, the antidepressant and analgesic activities of the complex have been assessed in rats denoting a marked synergistic effect.
A marked synergistic effect (synergy coefficient of 192.0 ± 13.1%) is observed when the oxidation of acetic acid by hydroxyl radicals is performed together with the cathodic production of hydrogen peroxide.
A combination of NAIs and non-NAIs did not exhibit a marked synergistic effect against the R292K variant.
Thus, the combination of RNAi of HIF-1 α and TAE had a marked synergistic effect on tumor growth inhibition [ 106].
Nonetheless, U0126 treatment did elicit a marked synergistic effect on LY294002-induced anoikis, reducing Tpr-Met-IEC-6 cell viability to levels well below those seen upon treatment with the PI3K inhibitor alone.
Rather than preventing transcription of these oestrogen responsive genes, TPA alone increased pNR2 and pNR100 levels in MCF-7 cells and the combined effect of oestradiol and TPA had a marked synergistic effect in increasing the transcript levels of these genes.
However, the combination treatment of DAC with sunitinib or axitinib exerted marked synergistic effects on proliferation inhibition.
To date, a number of in vitro investigations of RF-induced genetic effects in human and other cell types have been conducted, most of which have indicated no evidence of in vitro RF-induced genetic damage at nonthermal exposure regimes or marked synergistic or additive effect with another environmental agent (mutagen/carcinogen) (Meltz 2003; Verschaeve 2005; Vijayalaxmi and Obe 2004).
Gamma radiation showed synergistic effect with AgNOs revealing marked increase in apoptotic cells.
Interestingly, we observed a synergistic effect on this epigenetic mark when vorinostat (50 nM) was administered in combination with tadalafil (50 and 200 nM: Fig. 1b).
Therefore, the hypothesis that marked pulmonary functions impairment in transit workers was due to the synergistic effect of air pollutants and severally mutually inclusive factors is substantiated.
