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SEPT2 function is dependent of the formation of core oligomeric complexes with SEPT6 and SEPT7, and this septin heterotrimer is a recognized regulator of microtubule stability, with septin depletion resulting in a marked stabilization of microtubules and mitotic defects in vivo [ 1, 33].
MKK62E co-expression caused a marked stabilization of the β-globin-IL-24 chimeric mRNA.
In summary, our data support a model for LFA-1-regulated, Vav-1, Rac1 and Rac2, MKK3 and p38MAPK dependent HuR modulation, resulting in marked stabilization of ARE-bearing transcripts, including those encoding IFN-γ and TNF-α.
In parallel to pH correction, a marked stabilization of hemodynamics was observed.
TMAO was used due to its marked stabilization of α1-antitrypsin at high concentrations [ 35], as well as representatives of two other classes of osmolyte, sucrose (a polyol) and sodium sulfate (a kosmotropic salt).
By contrast, depletion of GNL2 or SEC13 led to a marked stabilization of a PTC-containing β-globin mRNA, confirming that both GNL2 and SEC13 act in the NMD pathway (Fig 4D).
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The evolution was marked by the stabilization of lesions in 15 cas(42,85 %) improvement in 10 cases (28.57 %) and worsening of lung damage in 10 (18.8 %) patients.
The post-D3 stage was marked by the stabilization of prograde garnet + quartz at upper amphibolite facies (650 ± 50 °C and 4.5 ± 0.5 kbar) conditions replacing syn-D2 3 hornblende/biotite + plagioclase assemblages in anorthosites, foliated granites and granulite enclaves, and the re-stabilization of a two-pyroxene + plagioclase assemblage at the expense of hornblende in mafic granulites.
That marks stabilization after a swoon in July, but the gauge has been stuck in a rut for the better part of a year, offering a glaring reminder that the recovery will not be led by consumers.
Previously we found marked prolongation of CP speckle retention time upon stabilization of F-actin induced by Jas.
The move by Eni, the largest foreign player in the Libyan oil industry, marks an important step toward the stabilization of the country's economy, which relies heavily on oil revenue.
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