Sentence examples for marked sensitisation from inspiring English sources

Ax-mock infection alone did not produce marked sensitisation in either of the two cell lines in the range of 2 6 Gy.

However, this marked sensitisation was not observed for the siRNA/control-transfected cells.

The MGMT inactivation by PaTrin-2 in MCF-7 cells resulted in marked sensitisation to temozolomide growth inhibition.

Upon stimulation, Bcl-2 was interacted with Keap1 and then rapidly degraded, leading to marked sensitisation of the cells to TNF- α- or staurosporine-induced apoptosis.

In vitro, reversal of the resistant profile of our model was achieved, with increases in both cell death and apoptosis induction, as well as marked increases in sensitisation (e.g., +80% at IC20) of the SW620 cells to 5-FU.

Sensitisation: nociceptors become sensitised following acute tissue injury, resulting in an ongoing discharge and hyperexcitability (peripheral sensitisation); prolonged nociceptor discharge enhances the response of dorsal horn neurones to afferent stimuli and expands the dorsal horn neurone's receptive field (central sensitisation), leading to allodynia without marked sensory loss.

Consistent with this result, our analysis of doxorubicin in combination with the MDM2 p53 antagonists demonstrated that sensitisation was also not as marked as that observed for vincristine (Supplementary Figure 4 and Supplementary Table 2).

We found that a limited number of microRNAs exhibited marked up- or downregulation following early-life infection and sensitisation, for many of which the levels of expression were further changed following chronic challenge with the sensitizing antigen.

At day 49 of life, following recovery from neonatal PVM infection and sensitisation via the respiratory tract but prior to any inhalational challenge with OVA, there was marked (≥4.5-fold) upregulation of a limited subset of six miRNAs as assessed by analysis of microarray data (Table 1).

Each demobilized child soldier is issued a personal identification number and an ID card A sensitisation briefing on expected social behaviour and standards (known locally as tarbia), peace and civic education, and the signing of a code of conduct by each former child soldier marks the end of the demobilization process in each community.

Table 6 Subdivisions of the skin sensitisation data set into binary classes.