Sentence examples for marked selectivity for from inspiring English sources

Substitutions on the aromatic ring of the compounds produced compounds that displayed marked selectivity for α4β2 or α4β2α5 nAChRs.

Therefore, the discovery of endocannabinoid system has prompted the development of a range of novel cannabinoid receptor agonists and antagonists, some of which show marked selectivity for CB1 or CB2 receptors.

Taken together, the data suggest that compound 1 displays marked selectivity for cancer cells over normal cells.

Allosteric inhibitors of MEK are particularly promising as they exhibit marked selectivity for MEK over other protein kinases.

BDP5290 demonstrated marked selectivity for MRCKβ over ROCK1 or ROCK2 for inhibition of myosin II light chain (MLC) phosphorylation in cells.

MIP has a marked selectivity for dimethoate compared to other structurally related organophosphorous pesticides.

Of note, we observed marked selectivity in P2 preference for falcipains using small peptide substrates.

The sensor exhibits marked selectivity and sensitivity towards Fe3+, with a chelation-induced "off-on" response.

CGP 20712A and ICI 118551 clearly demonstrated marked selectivity in the rat studies.

Representative compounds exhibited marked nuclear receptor selectivity for PPARα and PPARδ.

The sensors showed marked humidity selectivity.