Sentence examples for marked responsiveness from inspiring English sources

Marked responsiveness of p50α to insulin suggests that this adaptor plays an important role in the activation of hepatic PI3K [ 21].

Note the indifference of roGFP2 and the marked responsiveness of Grx1-roGFP to oxidized glutathione.

With regards to the promoter activities of the CRELD2- ALgenegene pair, the entire intergenic region hardly responded to Tg, whereas the CRELD2 promoter constructs of the proximal region containing the ERSE motif showed a marked responsiveness to Tg.

However, these NK cells had a more marked responsiveness as demonstrated by a larger fold increase in cytotoxic function (upregulation of CD107a) when a stronger NK-cell stimulus was employed (Fig. 4).

Moreover, the high over-transcription we observed at 6 hours post-exposure for the insulin-like growth factor 1 binding protein (IGFBP-1) repressed by insulin in physiological conditions [ 41], indicated a marked responsiveness of cell receptors liable to early IR syndrome within a short exposure period.

PPARγ is highly expressed in immature dendritic cells (IDCs) derived from primary human blood monocytes and mediates marked receptor responsiveness, with strong ligand-dependent induction of aP2 expression in these cells (Szatmari et al., 2004).

It includes a measurement of tumor response after preoperative therapy: grade 1, good responsiveness (tumor is sterilized or only microscopic foci of adenocarcinoma remain); grade 2, moderate responsiveness (marked fibrosis but still with a macroscopic tumor); grade 3, poor responsiveness (little or no fibrosis with abundant macroscopic tumor).

Advanced primary tumours showed marked variation in responsiveness and some showed a difference in response to different drug groups.

A gradual drop in granule cell responsiveness marked the transition into the second period of the first phase (Fig. 6B, C).

In the context of VEGF levels, which are increased in papillomas, but not as much as in invasive tumors [ 27], normal Dll4/Notch signaling levels act as a suppressor of VEGF signaling and even a 50%% decrease can result in a change of VEGFR2/VEGFR1 ratio and marked increase in responsiveness to VEGF levels.

Unfortunately, studies on isolated and cultured SC or SC-lines have proven of limited use since these cells appear to de-differentiate in the absence of GC, exhibit a marked reduction in androgen responsiveness and lack the expression of prototypic androgen-regulated genes such as reproductive homeobox 5 (Rhox5) [16], [16].