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The most strongly represented metabolic function was carbohydrate metabolism in each the 1.8 and 7.2 mg/L RDX exposures, with additional marked representation of transcripts involved in energy and amino acid metabolism (Table 1).
The data further define marked representation of IFN-γ responsive genes and a prompt inter-organ communication as a hallmark of an early local tissue response to infection.
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When these genes were assigned to functional categories, and the relative representation of those functional categories was plotted across the span of the day, most functions had a marked representation for a particular time of day (Figure 4).
Such suppression and enhancement (Fig. 3d) together account for the marked over-representation of the exposed orientation, observed in the orientation polar maps (Figs.
When goggle rearing (GR) started at P16-P30, 2 weeks of GR induced a marked over-representation of the exposed orientation, and 2 more weeks of GR consolidated the altered orientation maps.
There is a marked under-representation of countries in high-impact general medical journals.
In mammals, a marked under-representation of introns in the 3'UTRs may be explained by the requirements for nonsense-mediated decay (NMD) [ 38, 39].
This cluster includes a marked over-representation of those aged 80 84 years and those who either never drink or drink but do not binge drink and are non-smokers.
One of the most striking compositional abnormalities in DNA sequences of mammalian and other vertebrate genomic DNA sequences is the marked under-representation of CpG and over-representation of CpA and TpG dinucleotides.
They found a marked over-representation of Prevotella species, in particular P. copri, in most, though not all, members of the recent-onset rheumatoid arthritis group, but in few of the individuals in the other three groups.
Finally, we determined a set of 'CNS-signature' genes that uncover characteristics of several common neuronal processes in the CNS, with marked over-representation of specific features of synaptic transmission, ion transport and cell communication, as well as numerous novel unclassified genes.
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