Sentence examples for marked reduction in the expression of from inspiring English sources

HIF1-deficient T cells display a marked reduction in the expression of IL-17 and Th17-signature genes.

Differentiation in 50 and 75 nM PD173074, however, resulted in a marked reduction in the expression of all gene markers, suggesting that commitment to primitive streak intermediate, during early mesoderm formation, is inhibited in the presence of PD173074 (Figure 2D).

A marked reduction in the expression of TLR2 was observed in M cultured with MSC compared with M cultured alone: % inhibition in the expression of TLR2 = 78±16 (n = 4, p<0.05 vs controls).

All type B clones and the majority of type A clones in the CB (16 clones, 5 brain hemispheres) abolished or showed a marked reduction in the expression of the pan-neuronal marker ELAV, indicating that the generation of neurons in these clones was inhibited (Fig. 4 M O).

KO mice also show marked reduction in the expression of enzymes involved in oxidative phosphorylation.

Silencing of E1A resulted in a marked reduction in the expression of all other genes (Fig. 2B).

Further studies demonstrated that curcumin showed a marked reduction in the expression level of FABP5 and PPARβ/δ.

Correlating with these changes, there was a marked reduction in the expression levels of several anti-apoptotic proteins including BCL-2, BCL-xL and survivin.

There was a marked reduction in the total protein expression of AKT2, PRAS40 and GSK3A when miR-184 was overexpressed (Fig.  4d).

Of note was the marked reduction in the level of 5-LO Xgene expression.

As expected, given its pro-apoptotic role during thymocyte development, Nur77 over-expression led to a marked reduction in the numbers of mature T cells in the periphery.