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The activation of PLC elicits marked redistribution of the PH-GFP signal from the plasma membrane to the cytosol.
Vasopressin caused marked redistribution of splanchnic regional and microcirculatory blood flow, including a significant decrease in portal, pancreatic, and renal blood flows, whereas hepatic artery flow remained virtually unchanged.
Treatment of these cells with SKi causes a marked redistribution of HER2, which localised into cytoplasmic punctuate bodies and accumulated into an unidentified intracellular compartment.
As expected, a weak but uniform Gag signal was present in vector-only transfected cells (Figure 1Aa) and transient HLA-DR expression induced a marked redistribution of Gag as indicated by a dense, punctuate Gag staining pattern (Figure 1Ad).
In HEK-293T cells expressing HLA-DR, there was a marked redistribution of Gag to intracellular compartments, and reduced virus release at the PM; mature virus budded into HLA-DR containing multivesicular bodies and was retained [8].
Following treatment with fusogenic reagents a marked redistribution of Plin A-YFP over the surface of the LDs was observed, with the formation of dense patches of Plin A-YFP prior to LD fusion (Fig. 4b, Video S8), or the directional redistribution of Plin A-YFP on LDs that did not subsequently undergo fusion for the duration of imaging (30 min) (Fig. 4c).
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In summary, we investigated the process of the H3K4me2 mark redistribution during tissue specificity development for mouse brain tissue.
We investigated the process of the H3K4me2 mark redistribution during tissue specificity development for mouse brain tissue.
Note that (1) we did not use this term to reject the null hypothesis that it is zero, but to capture the amount of variation according to the model and (2) the term strain:mark:bin captures strain-specific redistribution of some marks along the gene, which is also relevant to divergence in chromatin pattern.
A complex and more precise redistribution of marks was also apparent on some nucleosomes of the alpha-specific SAG1 gene (Additional file 13).
Additionally, gap junction remodeling (GJR), a process marked by decreased expression and intracellular redistribution of Cx43, corresponds spatially to the central common pathway of reentrant circuits in the canine peri-infarct zone (30).
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