Sentence examples for marked predisposition from inspiring English sources

Fanconi anemia (FA) is a recessive disorder associated with progressive pancytopenia, multiple developmental defects, and marked predisposition to malignancies.

FA is associated with progressive pancytopenia, developmental defects, and marked predisposition to malignancies, especially acute myeloid leukemia and squamous cell carcinoma of the head and neck [ 1, 2].

These clinical presentations, which are secondary to sensitivity to ionizing radiation and a marked predisposition to cancer, were explicated in 1995 by Savitsky et al. as an autosomal recessive mutation in the Ataxia Telangiectasia Mutated (ATM) gene.

However, what exactly causes the marked predisposition for tissue deposition and rapid clearance from the circulation is unclear.

Werner Syndrome (WS) is an autosomal recessive segmental aging disorder associated with a marked predisposition to cancer and vascular disease [ 1, 2].

It was encouraging to see that young people who participated in this study showed a marked predisposition to listen to the person who needs help and then suggest professional help-seeking or even make an appointment for her to see a GP with her knowledge, consistent with the guidelines of programs like Mental Health First Aid [ 3].

Loss of WRN causes the progeroid disorder Werner syndrome which is marked by cancer predisposition.

The Diagnosis: Multiple endocrine neoplasia, or MEN, is marked by a rare inherited predisposition to develop tumors, or neoplasia, in various endocrine glands.

It is plausible that a predisposition toward NAFLD could reflect the presence of particularly marked IR and that the development and progression of the liver disease per se (with increasing inflammation and fibrosis) could further worsen IR and thereby increase CVD risk.

Probably the (unknown) aetiopathogenetic pathways marked by these antibodies have common components, including common genetic predispositions.

Werner syndrome (WS) is an autosomal recessive disorder marked by the premature onset of numerous features associated with aging and a predisposition to mesenchymal cancers [1].