Sentence examples for marked perturbation from inspiring English sources

These inflammatory molecules contribute to marked perturbation of paracrine dialogues between those cells, which contributes to altered AT biology, promoting, for example, local inflammation and metabolic alteration such as insulin resistance as well as increased remodeling and fibrosis (Dalmas et al. 2011).

Since the CF lung disease is characterized by poor Cl- secretion and water retention in the airways [ 74], it is likely that the estrogen-related disturbance in Cl- secretion via the Ca+2-activated channels and other pathways can cause marked perturbations in mucociliary clearance, and accumulation of thick mucus in the airway, resulting in disease progression [ 85].

We have described a decirculation process which marks perturbations of network structure that are necessary for nonlinear network dynamics to proceed from one circulating state (a limit cycle) to another stable state (a limit cycle or a fixed point).

Marked perturbations in the hormonal homeostasis developed early after tumour transplantation.

The amplitude onset duration of the perturbation event marked by the line with arrows is about 3 s and phase onset is about 0.9 s.

Thus, insulin resistance progressing to T2DM is marked by a broad perturbation of macronutrient intermediary metabolism.

Insulin resistance progressing to type 2 diabetes mellitus (T2DM) is marked by a broad perturbation of macronutrient intermediary metabolism.

In order to explain these observations, we first give the explicit expressions for the one- and two-photon absorption matrix elements: 3 4where the individual perturbations are marked by lowercase letters.

Furthermore, epidemiological data suggest marked susceptibility of the lung to perturbation by As, especially during prenatal and childhood development, which results in unprecedented rates of chronic lung diseases, notably lung cancer and bronchiectasis.

Similarly marked effects were noted for combined PRL/IL-13/MCP-1 perturbation, which resulted in marked changes in all downstream hub statuses and conditional probability values (Additional file 6).

Similarly, perturbation in the pattern of PP1γ expression is apparent in CIN2 lesions, and this becomes more marked as the lesions progress to CIN3, suggesting that perturbation in the pattern of PP1γ expression is an early event in the development of cervical malignancy.