Sentence examples for marked modification from inspiring English sources

It has been clearly documented that the remodelling of endothelial cells due to LSS is associated with an increase of proteoglycan distribution and marked modification of gene expression, resulting in protection of the endothelial layer from atherosclerosis [ 8, 9].

On the contrary, the third group of patients that never reached BNP <250 pg/ml at discharge displayed marked modification of the prognosis with high rate of complications, death, and rehospitalization.

The present study, demonstrating significant correlations between age and inflammatory mediators of the eicosanoid and MMP pathways in whole buccal saliva from healthy volunteers, points to a marked modification of the inflammatory state of the oral cavity associated with age.

OPN in concentrations from 1.59 to 3.82 μM caused a marked modification of crystal shape with increasing concentration.

For the strain secreting the cellulosomal form of Cel9A, the marked modification of the paper stripe occurred roughly 2 days in advance, with respect to the control strain.

From Figures 2(a) and 4, a marked modification of the time-related trends for several metabolites starting from the 12th hour after death can be evinced.

Differences on the absorption process were not found, however; marked modifications on the distribution process were eloquent.

Further investigation of minor variant models by Little et al. [ 6] did not suggest marked modifications to these conclusions.

The silencing of the SBEIIa gene caused marked modifications on amylose content, granule morphology and starch composition.

TEM analysis of these renal corpuscles showed marked modifications of the GFB, with shedding of podocytes, loss of the endothelial cell lining and massive disruption of the endothelial glycocalyx.

They also illustrate marked effect modification by age, as the association attenuated with increasing age.