Sentence examples for marked interindividual variability from inspiring English sources

Previous work has demonstrated marked interindividual variability in onset and rate of decline.

Numerous large clinical trials demonstrated the beneficial effects of RAS blockade on clinical symptoms and outcomes of patients with CKD; however, marked interindividual variability were detected in response to these treatments ranging from recognizable clinical benefit to non-detectable benefits or even serious adverse effects [12, 13].

The inhibitory effect of clopidogrel on platelet function shows marked interindividual variability.

Expression of OATP1B1, OATP1B3, and OATP2B1 at the mRNA and protein levels showed marked interindividual variability.

Marked interindividual variability was also obtained when only non-cholestatic liver samples (n = 117) were analyzed (Table S4A in Additional file 1).

Baseline pCO2 gap (piCO2-paCO2) was 1.91 ± 0.66 kPa and did not change during the study (ANOVA P = 0.44; Fig. 1) Marked interindividual variability was observed during gastric feeding mainly.

Studies in transplant patients have demonstrated marked interindividual pharmacokinetic variability, resulting in the widespread use of therapeutic drug monitoring based on whole blood concentrations.

Nevertheless, the study of Kleinsteuber et al. also demonstrated marked interindividual differences of miRNA candidate expression (up to 105-fold).

In addition, marked interindividual differences were noted among the patients: three of them had only one weak point, topic maintenance.

We have observed marked intercellular and interindividual variability in the expression pattern and abundance of NMDAR subunits in EPCs of healthy humans (Fig. 5, B and C).

While steady-state clearance had moderate (41.5% CV) interindividual variability, time-dependent clearance was more variable, with interindividual variability of 122% for CLT and 201% for kdes.