Sentence examples for marked inhibition from inspiring English sources

In in vivo studies, 8f showed marked inhibition of the growth of HCT116 xenografts.

In contrast, CLC intervention led to marked inhibition of S-phase DNA synthesis and 100% mortality by 120 h.

In GC+ synovitis, treatment with TACI Fc resulted in GC destruction and marked inhibition of IFN-gamma and Ig transcription.

In xenograft models, BI-2536 demonstrated marked inhibition of growth of SW-13 with less inhibition of H295R.

Additionally, marked inhibition was observed in the presence of 10 mM CoCl2 (63% residual activity), 0.1 mM CuCl2 (73% residual activity) and 0.01 mM ZnCl2 (59% residual activity).

Indeed, both BRO and thyme extract caused marked inhibition of 5-LO activity (Fig. 4a) corroborating the hypothesis that 5-LO activity is a pharmacological target of BRO.

Using full-length MYPT1 constructs phosphorylated by various kinases it was shown that Rho kinase gave marked inhibition; ILK produced an intermediate level of inhibition, which was considerably reduced for the Thr 695 -->Ala muThr 695 -->Alahad no effecThr 695 -->Ala

When p53 was upregulated, we observed marked inhibition of RASSF1A expression, due to p53 binding to the RASSF1A promoter.

When tranilast was added to cultures of MDA-MB-231 or BT474 breast cancer cells at 200 µM there was marked inhibition of colony formation (Fig. 1A C).

ARF causes marked inhibition of fin regeneration.

GPA causes marked inhibition of [C]CT uptake by TM-BBB cells as reported elsewhere [ 62].