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In addition, a marked increased of yellowness values (control: 2.25, 0.5% CLC: 5.44) was observed when the concentration of CLC increased (p<0.05).
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Moreover, augmented expression of p21 and marked increased cleavage of PARP was evident in the mice that received the combination treatment, confirming in vitro data.
Cav-1−/− BM LSKs contained increased frequencies of LT-HSCs, but a marked increased frequency of ST-HSCs.
Treating rats with CP caused marked increased expression of BCL-2 in hepatocytes (Fig. 3b).
Moreover, immunohistochemical demonstration of antiapoptotic protein BCL-2 showed that treating rats with CP caused marked increased expression of BCL-2 in hepatocytes.
The apparent marked increased incidence of retinopathy in the validation population is due to the fact that in this population the definition of retinopathy included background retinopathy whereas in the initial population background retinopathy was excluded from this diagnosis.
However, other studies have shown that patients with SLE have a marked increased risk of CVD as compared to the general population [ 2, 15, 50].
Patients with burns over 80% TBSA had persistent and marked increased levels of IL-8, IL-6, monocyte chemoattractant protein-1 and TNF.
The observed increased prevalence of infant respiratory illness is consistent with As-associated adult non-malignant lung disease [ 35, 42] and marked increased risk of such disease following early-life exposures [ 43].
Central administration of MPTP showed significant impairment of motor behavior and marked increase of oxidative damage and neuro-inflammmation in rats.
Central administration of MPTP showed significant impairment of motor behaviour and marked increase of oxidative damage LPO and GSH in striatum and cortex.
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