Sentence examples for marked increase in the expression of from inspiring English sources

Interestingly, the same authors have found that in fibrotic livers there is marked increase in the expression of both PDGFα receptor and its ligand PDGF AA [ 33].

In conclusion, although there is a basal 12/15-LO 12/15-LO in the wild-type mouse prostactivityre in a marked increase in the expression of 12/15-LO with TRAMP PCa progression, paralleling our previously reported increased expression of the ortholog 15-LO-1 in high-grade human PCa.

Interestingly, FGF21-treated mice show a marked increase in the expression of the key thermogenic genes Ucp1 and Dio2 in inguinal WAT (iWAT), whereas Fgf21-deficient mice show an impaired response to cold stress due to diminished thermogenic activity (Fisher et al. 2012).

Previous studies have demonstrated a marked increase in the expression of pro-inflammatory genes in adipose tissue in obesity [12], [13].

Both agonists also caused a marked increase in the expression of SREBP1c, which is compatible with the earlier reported role of SREBP1c in controlling SCD expression downstream of PPARα and LXR [22].

Contrarily, a marked increase in the expression of Fas and in the percentage of Fas-L positive neoplastic cells was recorded when cells were cultured with specific Sags (Figure 5B-E).

We also observed marked increases in the expression of several p53 target genes known to be involved in the regulation of cell cycle arrest and apoptosis.

Murasaki et al demonstrated marked increase in the expression levels of Pim-1 following overexpression of cardiomyocytes, while knocking down Akt reduced Pim-1 [ 41].

Quantitative PCR analyses showed marked increases in the levels of expression of TLR9 in IPF SLBs relative to the levels of TLR9 expression detected in normal margins from resected lung tumors.

There were marked increases in the infiltration of mononuclear cells.

This marked increase in OPN expression can be explained in two ways.