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Animal models, particularly mouse models, have been extremely instructive in elucidating the functions of human ABC transporters but there is often a marked inconsistency between human and mouse pathologies, for example in CF and X-linked adrenoleukodystrophy [ 30, 40].
Similar(59)
For example, Lajiness et al. report a study of medicinal chemists at Pharmacia, who were asked to review lists of compounds in order to assess their potential as leads in a drug discovery programme [10]; not only were there marked inconsistencies between the chemists, but even the same chemist might give different assessments on different occasions.
Even after separation into weight categories and correction for dietary intervention there are marked inconsistencies between, and sometimes within studies on the effect of exercise on plasma lipids.
While these associations were not statistically significant, there are marked inconsistencies between the race‐specific rates and associations with health behaviors.
In 2012 HMC published a report exposing the "truly shocking" failings in the way exams are marked; the union criticised weaknesses including poor marking, inconsistencies between exam boards and fluctuating grade boundaries.
The survey findings demonstrate a lack of professional consistency and clarity regarding the suitability of reflexology for cardiac patients, marked inconsistencies in the heart reflex point placement and inconsistency in reflexologists treatment decisions for perceived heart imbalances.
His time with the Phillies was marked by inconsistency.
Although there was success, the Fassel era was also marked by inconsistency, and he was fired after the 2003 season.
Marker inconsistency was also observed in a few regions, mostly caused by duplicated marker loci or segregation distortions [ 68].
There was marked between-study heterogeneity.
There are marked differences between these parts.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com