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According to many studies, migraine and other disorders lead to widespread suffering, reduction of quality of life, and marked impairment of participation, both in work and social activities.
Compared to transgenic flies overexpressing wild-type deltasg, or the standard laboratory strain w(1118), Drosophila expressing deltasg(S151A) developed marked impairment of systolic function and significantly enlarged cardiac chambers.
In the "Within" group, the significant increase of lung weight at the end of the experiments was associated with sharp deterioration of gas exchange and marked impairment of lung mechanics.
Patients were excluded if they either had marked impairment of communication or they had another neurological condition.
They may experience marked impairment of quality of life impacting on activity, symptoms and participation in daily life [ 15].
Moreover, murine embryos expressing a hypomorphic allele of the Notch ligand Dll1 displayed marked impairment of skeletal muscle formation.
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Both + dP/dtmax and –dP/dtmax began to decrease significantly in group C, and were sustained in group D, which suggested marked impairments of both systolic and diastolic capabilities of the diabetic myocardium.
Therefore, we cannot exclude the possibility that patients with marked impairments of movement sequencing abnormalities had such marked impairment present from the beginning of the illness.
There was marked impairment in the ability of CpG DNA treated pDC from HIV-1 infected individuals, regardless of their therapy status, to activate NK cells with respect to expression of CD69, CD25, and CD107a compared with healthy controls (Figure 2).
This participant showed marked impairment in both brainstem processing of "da" and pitch contour of "ya" and significant improvement in pitch processing after training relative to the control group (see Figure 3).
Studies of SCA7 mice uncovered marked impairments in oxygen consumption and respiratory exchange.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com