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Bowen et al found that 48% of GPs were not confident in diagnosing CFS/ME in adults and 51% could not identify 3 key clinical features (fatigue, symptom exacerbation on over-exertion and marked fluctuation of symptoms) [ 17].
Excessive withdrawal of groundwater for irrigation during the dry season causes a marked fluctuation of water table.
Because we observed a marked fluctuation of PPL expression in mouse liver in association with the bile acid receptor farnesoid X receptor (FXR) and cholestasis, we sought to characterize the role of PPL in the liver and determine its contributions to the etiology and pathogenesis of cholestasis.
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From middle to Late Pliocene time marked fluctuations in the abundance of cool and warmer water plankton taxa occurred, corresponding to a time of global marine δ18O fluctuations and generally heavier δ18O values associated with the expansion of the Antarctic ice and Northern Hemisphere ice sheets.
In relation to intakes to pre-registration education, the scenarios are developed from a situation in which there have been marked fluctuations in the numbers of student nurses and midwives being trained over the last 20 years, with a sense of "boom and bust", and with a recent trend towards reduced funding for intakes.
This is possibly because the mercury arc lamp used as a source in many epi-fluorescence studies shows marked fluctuations such as those observed by us in our experimental design process, making quantification of the type done here difficult [ 14].
Many mammalian species undergo marked fluctuations in reproductive physiology and behavior on a seasonal basis.
Although there appear to have been marked fluctuations in folate intake between 1960 and 2008, the overall consumption has been decreasing.
Therefore they show marked seasonal fluctuations in common physiological processes – including synthesis and accumulation of phenolic compounds [ 47].
Chronic illnesses are marked by fluctuations and variations over time.
Lewy bodies composed in part of alpha-synuclein aggregates are the hallmark of Lewy body disease, presenting in prototypic cases with visual hallucinations, extra pyramidal symptoms, and marked clinical fluctuations [ 54].
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