Sentence examples for marked elevation in the expression of from inspiring English sources

Furthermore, qPCR-based determination of CXCL8 mRNA confirmed a marked elevation in the expression of this NF- κB-transcriptional target in PC3 cells relative to DU145 cells (P<0.001).

However, in H. pylori-induced atrophic gastritis there was a marked elevation in the expression of iNOS compared to uncomplicated gastritis.

The lack of major abnormalities is attributed to a marked elevation in the expression of matrix metalloproteinases, for example, MMP2 and MMP14 in the Hpse-KO liver and kidney.

Despite complete lack of heparanase gene expression and enzymatic activity, the mice developed normally, were fertile and did not exhibit apparent anatomical and functional abnormalities, presumably because heparanase deficiency was compensated in most organs (i.e., liver, kidney) by a marked elevation in the expression of matrix metalloproteinase i.e., MMP-9 and MMP-14 family members.

With marked elevation in the serum concentration of noradrenaline, accurate estimation of blood pressure and cardiac output is essential for successful anesthetic management.

Compared to control, C/D box analysis revealed marked elevation in the number of UG dinucleotides and D-box sequences in NaF exposed HOS cells.

The non-diabetic group receiving memantine showed marked elevation in levels of immunostaining, becoming dense and more widespread in the enlarged glial cells.

Cytokine antibody array data showed that seven inflammatory mediators were elevated out of the 40 tested, including marked elevation in interleukin (IL -6 and IL -6secretion.

While the signaling mechanism responsible for the inductive effect of UA on MICA/B expression were not identified, marked elevation in MICA/B protein levels were clearly evident that were inhibited by treatment with allopurinol in vitro.

Consistent with previous studies [ 13, 31], in the present study, ISO administration to rats caused marked elevations in all of the serum cardiac marker enzyme activities.

Marked elevation in expression of the female predominant cytochrome P450 (CYP)2A4 (25-fold), and significant increases (25-fold-fold) of female dominant CYP2B9 (2.6-fold) and CYP2D9 were evident.