In the present study, there is marked differentiation between Central America and all four Amazonian population clusters.
The expression is particular high in tissues characterized by rapid proliferation and marked differentiation, and in tissues undergoing morphogenetic changes [ 9].
In comparison with control cultures in regular expansion media (Fig. 2e), marked adipogenic differentiation occurred in the presence of adipogenic induction media spiked with rabbit serum (Fig. 2f).
In contrast, K/R cells exhibited marked attenuation in differentiation and lipid accumulation compared with WT cells.
Studies have shown that MSCs isolated from inflamed dental tissues retained their regeneration potential, but they exhibited a marked reduction in differentiation potential, particularly for mineralized tissue [ 4, 7].
Our results demonstrate that seizures induce a marked change in the differentiation of ESNPs into neurons rather than astrocytes.
The b1000 images, by contrast, show little normal tissue differentiation but marked differences in signal between damaged and undamaged tissue.
ADAR1 deletion led to marked changes in intestinal differentiation, an expansion of transient amplification (TA) cells, and severe intestinal injury and inflammation.
In marked contrast, in patients with RPL11 mutation or following RPL11 depletion by specific shRNA, we identified a more pronounced phenotype: a greater extent of decrease in cell proliferation, delayed erythroid differentiation and marked increase in apoptosis.
Our analysis has focussed on the transcriptome switch that marks neural differentiation onset uncovered in this dataset.
