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Established SAR revealed marked dependence of the cytotoxic activity on the type of substituent on isatin and the length of carbon-bridge connecting isatin moiety with triazole ring.
Marked dependence occurred in 42% of controls versus 32% of intervention patients, and there was no significant change in functional scores in either group over time.
Note the marked dependence of response dynamics on the plant model.
In addition, S. pombe introns that were most highly dependent on the large subunit also exhibited a marked dependence on the small subunit (Webb et al. 2005).
The pore-size-dependent flow stress of replicated microcellular aluminium exhibits a marked dependence on the leaching process used to produce the foam when the pore size is below roughly 100 μm.
The sputtering of surface atoms in these samples shows a marked dependence on their surface architecture.
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The economies of the region are marked by dependence on the export of a few commodities, commonly agricultural, and consequently are extremely vulnerable to external economic events.
They are marked by dependence on technology, delaying of adulthood, a casual approach to life and placing a higher value on self-fulfilment than previous generations.
Recently, marked oxygen dependence of respiration by isolated mitochondria after exposure to prolonged hypoxia has been described.
Usually, marked temperature dependence such as observed for these peptides is indicative of uptake by endoctytosis [ 15].
However, it is also clear that pairs of homologous chromosomes that fail to establish a chiasmate link (non-exchange chromosomes), and thus will present as univalents at MI, are also associated with a preponderance of maternal MI errors but do not have the marked age dependence [ 23 25].
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