Sentence examples for marked changes were from inspiring English sources

Histologically, marked changes were noticed in testes of PTU-treated mice; immunohistochemical and western blot analyses of testes in treated mice also revealed marked decrease in the expression of THRα1 at both age groups.

Marked changes were observed in the most recent surveillance, as the PCV7 coverage increased.

Despite similar specific growth rates, marked changes were observed at the molecular level.

However, marked changes were observed in specific nuclei of the hypothalamus that regulate various neuroendocrine functions such as feeding, reproduction, stress, and circadian activity.

In Denmark and Sweden we found no significant changes in the overall use of antibiotics, but marked changes were found related to the choice of antibiotics.

Particularly marked changes were obtained in P450s identified as CYP2B10 (corresponding to the upper band and CYP2B9 to the lower band according to the findings of Li-Masters and Morgan [ 20]) and CYP3A11.

On behalf of the exam boards, the Joint Council for Qualifications said most of the marking changes were "relatively small" – between one and two marks.

No marked changes overtime was observed in the different social classes, or in the overall incidence rates in the population.

In addition, we recently showed in patients with rheumatoid arthritis that marked changes can be detected in the synovial tissue as soon as 48 hours after the first infusion of infliximab [ 35].

Although symptoms were reported as being marked changes in health, only haemoptysis was interpreted as serious enough to warrant urgent medical attention by patients [ 6].

Intriguingly, besides growth and invasion defects, marked morphologic changes were observed for the established PRL-3 knockdown cells.