Sentence examples for marked changes occur from inspiring English sources

The fact that diabetes induces neuropathy and that in a proportion of patients this is accompanied by pain despite the loss of input and numbness, suggests that marked changes occur in the processes of pain signaling in the peripheral and central nervous system.

Marked changes occur during the procedure, especially at the time of reperfusion [ 16, 17].

Marked changes occur early during treatment in both anatomic and functional imaging readouts, although the magnitude of change between fraction 11 and 21 timepoints was generally less than that seen at fraction 11 compared with baseline.

The data presented here confirms that marked changes occur early during treatment in both anatomic and functional imaging.

If no marked changes occur after further radiotherapy fractionation, an immediate shift to a combination therapy or surgical procedures would be the treatment of choice.

It is generally agreed that the most marked changes occur in the cellular immune response reflecting profound alterations in T cells.

However, marked changes occurred in the levels of activated pMEK (S217/S221).

For example, before the infamous collapse of the northern cod off Newfoundland and Labrador, marked changes occurred in key life-history traits such as maturation schedule (Olsen et al. 2004).

Over the last several decades, marked changes have occurred in the family structure in many societies by various factors, such as migration, economic fluctuations, and instability.

The immune system is particularly challenged in transition cows as marked physiological changes occur in this period which are driven by late gestation, partus and onset of lactation.

Implications and future directions These findings indicate that, upon latent infection with T. gondii, marked neuroanatomical changes occur in CNS regions that are relevant for normal behavior, and establish a murine model for translational studies of chronic toxoplasmosis.