Sentence examples for marked by substantial from inspiring English sources

The past 10 years have been marked by substantial excitement — and more than a little hype — over the nation's possibilities.

It helped Livingstone that his time at City Hall was marked by substantial fresh investment in the capital's transport network, notwithstanding his losing battles with Gordon Brown over ill-fated public-private partnership financing schemes.

But Putin's rule, especially since his return to the Kremlin in 2012, as President, has been marked by substantial empowerment of security élites, and a crackdown on free expression.

For instance, the Pleistocene glacial epoch (about 2,600,000 to 11,700 years ago) was marked by substantial variations in the global extent of glaciers and ice sheets.

Mrs. Clinton's aides argued that the calendars backed up her argument that her time as first lady was marked by substantial foreign policy experience, although they emphasized that the calendars only show her public events and do not reflect the wide sphere of influence she had with her husband and others.

Methadone has a complex pharmacokinetic profile marked by substantial interindividual pharmacokinetic variability and is associated with numerous drug interactions [3].

Aging is marked by a substantial decrease in the regenerative potential of several cell types, including immune cells and skeletal muscle cells [ 1, 2].

In this respect it should be considered that the transition of pre-60S particles from the nucleolus towards the nucleoplasm is marked by a substantial reduction in complexity with several nucleolar factors being released [15].

Her death in 1922 was marked by the appearance of substantial obituaries in both Mind and the Proceedings of the Aristotelian Society.

La Tène period is marked by drier conditions and a substantial increase in Alnus.

Like the VZ model before it, Holden with the VE have continued to moderate the long-standing tradition of implementing substantial updates marked by the frequent use of new model designations (such and VT, VX, and VY) successively interspersed with "Series II" and occasional "Series III" revisions.