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Ms. Couric and CBS are now negotiating how and when to end her five-year run as anchor, one marked by early criticism, later journalistic successes and disappointing ratings over all.
Then, in a performance marked by early jitters that sent a few throws sailing high and later by three touchdown passes, Roethlisberger led the Steelers to a 28-10 victoverover the Cleveland Browns.
Though his two plays ("This Is Our Youth" and "The Waverly Gallery") are both autobiographical, "You Can Count on Me" is not based on his own life, he said; he was fascinated by the idea of siblings, marked by early tragedy, who have pursued opposite paths.
Lateglacial climatic amelioration was marked by early growth of peat (ca 16,500 cal. yr BP).
T cell receptors activated the T cell proteome and phosphoproteome with discrete kinetics, marked by early dynamics of phosphorylation and delayed ribosome biogenesis and mitochondrial activation.
The autism spectrum disorders (ASD) are a complex group of disorders defined by deficits in social interaction, communication and a pattern of circumscribed interests and repetitive behaviours [1] Fundamentally neurobiological in origin, ASD is marked by early developmental onset [2] and is among the most heritable of psychiatric disorders [3], [4].
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Autism is a neurodevelopmental disorder marked by early-onset impairments in social interaction and communication, and unusually restricted, repetitive behavior and interests [ 1].
Specifically, we found that genes marked by early-only ZEB1 binding (≤ 10 kb distance, 'Materials and methods') were much more likely to have low expression in pre-adipocytes or to be repressed upon differentiation (clusters '1' and 'Low').
Their problems cross generational lines as well — young parents are themselves still other people's children, and they are marked by that early experience as well as by their ongoing relationships.
He is apt to stammer and to stick in his rut, having been marked by the early death of his mother and constrained by everything that is expected of him.
But he seems also to have been the Knox most marked by the early death of his mother, when he was eleven, and by the isolation of his schooling.
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