Sentence examples for marked and widespread from inspiring English sources

EEG evidenced marked and widespread slow bioelectric abnormalities.

Strikingly, marked and widespread signs of dysplasia, with nuclear pleomorphisms and initial loss of normal architecture, heralding malignant transformation, were scored in all the mutant mice exposed to ethanol, but not in the control-fed littermates nor in ethanol-fed normal mice.

Similarly, the Ktrans maps from patient 26 indicate marked and widespread reduction in perfusion of an ovarian carcinoma metastasis at 6 days following CYT997 administration.

In our study, the marked and widespread expression of podoplanin in lining layer cells in RA was not restricted to the apical cell surface.

With Cd-MEC co-culture, SCs showed a marked and widespread increase in VIM protein, a mesenchymal cell marker, and increased VIM transcript.

This consisted of four categories: Grade 1, tumours showed invasive, well-delineated borders; Grade 2, infiltrating, solid cords, bands and strands; Grade 3, small groups or cords of infiltrating cells (n>15); Grade 4, marked and widespread cellular dissociation in a small group of cells (n<15) and/or in single cells.

Rather, the dating committee's memo states, "a recession is a period of significant decline in total output, income, employment and trade, usually lasting from six months to a year, and marked by widespread contractions in many sectors of the economy".

Our model was based on the viticulture of the Banyuls Collioures AOC area, which is characterized by small-scale vine-growers and marked by widespread involvement in cooperative systems.

The dictator, whose eight-year reign of terror in Uganda in the 1970's was marked by widespread killing and torture, was about 78.

In another study by the same group, oral inoculation of A. actinomycetemcomitans resulted in an intense and widespread migration of leukocytes to the gingival tissues along with marked alveolar bone resorption.

Many are harmless and widespread.