Sentence examples for marked and persistent from inspiring English sources

Cardiopulmonary bypass induces marked and persistent depression of circulating thyroid hormones in infants and children, possibly contributing to postoperative morbidity.

Thus, 10 mg/kg of bupropion had no effect on the DA and NE concentrations, while 30 mg/kg of bupropion induced transient but significant increases (about 240% of the baselines), and 100 mg/kg of bupropion induced marked and persistent increases (over 600% of the baselines) in the DA and NE concentrations.

Some people with asthma rarely experience symptoms, usually in response to triggers, whereas others may have marked and persistent symptoms.

Second, in a model of genetic deficiency of the anti-apoptotic protein BI-1 (Bax inhibitor-1), which regulates the UPR by inhibitory association with IRE1α, there was marked and persistent XBP1 splicing despite increased sensitivity to ER stress-mediated apoptosis [45], [46].

But throughout this period infant mortality has shown marked and persistent socioeconomic gradients within countries, even in countries with universal healthcare access [ 2- 4].

The term HE should be used when marked and persistent eosinophilia has been documented or marked tissue eosinophilia is observed (Table 1) [ 9].

American history has been marked by persistent and determined efforts to expand the scope and inclusiveness of civil rights.

He suffered severe anxiety starting when he hit puberty at age 11 and was eventually diagnosed with gender dysphoria, a serious medical condition marked by persistent and clinically significant distress caused by incongruence between an individual's gender identity and that individual's sex designated at birth.

The most-marked and persistent differences were between the CMhigh and BM children with a maximum of a +0.70 SDS at 18 mo of age (Table 2; P < 0.0001) with differences persisting until 10 y of age (all P < 0.01 except at 7 y).

Generalized Anxiety Disorder (GAD) is a common mental disorder marked by persistent anxiety and worries, which are excessive and difficult to control, as well as multiple psychological and physical symptoms [ 1].

Generalized Anxiety Disorder (GAD) is a common mental disorder in the primary care setting, marked by persistent anxiety and worries.