Sentence examples for marked alteration in from inspiring English sources

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In 1970, Haas showed marked alteration in growth direction and facial morphology as a result of orthopedic therapy [5].

The epigenetic factor, especially DNA methylation is the most important aspect of behavioral disorders with marked alteration in the DNA methylation pattern in the brain which leads to memory formation (Day & Sweatt, 2010).

indica cultivars in which mPing can be efficiently mobilized and marked alteration in cytosine methylation of various types occurs.

Collectively, these findings indicate marked alteration in cardiac gene program in diabetic heart and therefore, augment the need to explore the modulators of gene expression in diabetic heart.

This set of experiments also revealed a marked alteration in the levels of the Wnt pathway proteins.

Sepsis leads to endothelial damage, marked alterations in blood flow distribution and altered tissue oxygen metabolism, which are associated with high mortality rates among critically ill patients [ 1- 3].

As in adults, septic shock in pediatric patients induced marked alterations in immune parameters in accordance with the occurrence of a state of immunosuppression.

Importantly, marked alterations in metabolic pathways in response to the intracellular environment were also evident such as elevated levels of glycogen biosynthesis and mixed acid fermentation enzymes.

Consistent with findings in mice, marked alterations in nuclear envelope morphology, abnormal localization of RanGAP1, and nuclear accumulation of mRNA were found in cortex of Huntington's disease patients.

The present study was designed to study aluminum chloride which caused marked alterations in biochemical parameters such as glutathione peroxidase, catalase, superoxide dismutase, and TBARS in brain tissues of mice.