Sentence examples for marked adverse from inspiring English sources

Modern neuropsychopharmacology commenced in the 1950s with the serendipitous discovery of first-generation antipsychotics and antidepressants which were therapeutically effective yet had marked adverse effects.

In contrast, the AgNPs induced marked adverse effects on cell viability and could induce changes in cell shape, decrease cell viability, increase lactate dehydrogenase release, and finally cause cell apoptosis and necrosis [3, 6, 50, 51].

PsO and PsA are common diseases that have marked adverse impacts on QoL.

Adolescents with depression and ≥ 5 somatic symptoms (23% of the depressed) had marked adverse adult mental health outcomes compared to the other groups (Table  2).

Because outlying values can have marked adverse effects on regression parameters, the data were subjected to a series of tests for influential values, specifically, Cooks distance, DFBETA, DFFIT, COVRatio, and HATvalue using the R statistical procedure "influence measures" (20).

Results show that treatments had no marked adverse effect on their activities.

No marked pharmacological adverse effects were observed at 25 μg NCFHEB/kg.

RCC is marked by adverse tumour biology and its CSS ranks lowest among urological malignancies [ 3].

The DPP-4 inhibitors, sitagliptin and vildagliptin, are generally weight neutral, and have less marked gastrointestinal adverse effects than the GLP-1 receptor agonists.

The year 2007 was marked by widespread adverse clinical responses to heparin use, leading to a global recall of potentially affected heparin batches in 2008.

An Efficacy Index of 0.25 (adverse effects outweigh therapeutic effects) to 4.00 (marked therapeutic effects, no adverse effects) relates therapeutic effects of the treatment to adverse effects of the treatment.