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There was marked abnormality of the substantia nigra which showed brown discolouration and had a gelatinous texture throughout (Fig. 1b, double arrow).
In addition, marked abnormality was seen on volitional single-fibre electromyography with two-thirds of potential pairs showing increased jitter or blocking.
A subsequent EEG five months later showed marked abnormality with no normal rhythmicity and intermittent projected activity consisting of high voltage delta and multifocal sharp waves in bursts with attenuation of faster frequencies.
Results: Perichondrially injured animals in the 4-week age group developed a marked abnormality in the shape of the cricoid cartilage in the injured region.
Intraductal carcinoma of the prostate (IDC-P) is an intraglandular/ductal neoplastic growth of glandular epithelial cells characterized by marked abnormality of the glandular architecture and/or cytological atypia that exceeds what is typically seen in high-grade prostatic intraepithelial neoplasia (HPGIN).
This did not reveal any marked abnormality in abundance and distribution for any particular cell type within the retina.
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(a) Representative histology (original magnification × 10) demonstrates marked abnormalities in alveolar development with decreased alveolar number, larger alveolar spaces, and increased cellularity.
In contrast, mice with low expression of the transgene had marked abnormalities in betaAR function, similar to the WT mice.
Hughes et al. [7] noticed that both EEG and QEEG reveal marked abnormalities in alcoholic subjects, which might result in increased slow activity or the converse, while Waite et al. [8] using QEEG techniques confirmed that slow waves dominated the brain of alcoholics.
We carried out electrophysiological recordings using hippocampal slices prepared from adult sandy mice and found marked abnormalities in monoaminergic modulations at the mossy fiber-CA3 synapse.
COMP and MATN3 mutations show marked abnormalities in hip and knee joints.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com