Sentence examples for mark of gene from inspiring English sources

Specifically, the tri-methylation of the fourth lysine on histone H3 (H3K4me3) is known as a mark of gene activation associated with promoters [43].

Since DNA methylation in regulatory regions is often a mark of gene silencing, we modified existing microarray-based assays to detect both methylated and unmethylated DNA sequences in the same sample, a variation we term the MAUD assay.

Similar results were seen for H3K9Ac, another mark of gene activation.

It is widely accepted that DNA methylation is a repressive mark of gene activity.

Similarly, level of RNAPII and H3K4 trimethylation (a critical mark of gene activation) were also decreased upon MLL4 knockdown.

The histone variant H2A.Z is a universal mark of gene promoters, enhancers, and regulatory elements in eukaryotic chromatin.

Bivalent marking of gene promoters occurs frequently in ESCs and typically is associated with important regulatory genes (for example, regulators of differentiation, tumor suppressors, and cell cycle regulators) [ 82].

We find that two well-described molecular marks of gene regulation, trimethylation of histone H3 lysines 27 and 4, display such an asymmetric distribution of detection between immortal chromosomes and mortal chromosomes in asymmetrically self-renewing mouse hair follicle-derived DSCs.

In contrast, H3K4me3, a mark distinctive of gene activation, was not significantly detected under any condition in the context of Asr1.

Genomic imprinting is the epigenetic marking of genes that results in parent-of-origin monoallelic expression.

One class of epigenetic mark with particular relevance to cancer is imprinting; the epigenetic marking of genes in a parent-of-origin specific manner within the germ cells [ 9].