Sentence examples for mark of active from inspiring English sources
Using a genome-wide approach, we examined the distribution of H4K5ac, a mark of active chromatin implicated in transcriptional re-activation of post-mitotic cells through gene bookmarking [ 26], and its role in regulating transcriptional activity following the establishment of contextual fear memory in the adult mouse [ 4, 13].
Misexpression in mutants is accompanied by an increase in the H3K4me3 mark of active chromatin at the receptor gene locus.
Here we used epigenomic profiling for H3K27ac, a mark of active enhancers, coupled to transgenic mouse assays to examine the genome-wide utilization of enhancers in three different mouse tissues across seven developmental stages.
As a result, it is believed that histone acetylation primarily results in a more "open" chromatin configuration, serving as a "mark" of active gene transcription.
Wouldn't such evaluative attitudes manifest themselves in the kind of practical action that Brady thinks is the mark of active evaluative attitudes?
The A. thaliana NORs in root-tip cells of 15 day old plants do not overlap with signals for H3K4me3, a mark of active euchromatin (Figure 2B, second row from top).
In general, one parental allele is modified with DNA methylation and histone modifications associated with silenced heterochromatin, while the other allele is modified with marks of active chromatin, such as H3K4me3, associated with promoter activity on this parental allele.
Similarly, H3K56ac is specifically located at gene promoters and shows preferential marking of active genes, suggesting that, like in yeast, it could facilitate rapid transcriptional activation (Williams et al, 2008).
States 8 and 10 had epigenetic marks of active genes (permissive states) and state 9 may designate bivalent/poised promoter regions (Fig. 2).
Tbx5-dependent ncRNAs were enriched for tissue-specific marks of active enhancers genome-wide.
Together, these data show that part of the FLC and FT chromatin simultaneously possesses the bivalent chromatin marks of active H3K4me3 and repressive H3K27me3.
