Your English writing platform
Discover LudwigExact(7)
In contrast, in the isogenic miR-200c/miR-141-negative mammary fibroblasts permissive histone modifications are absent, and the repressive H3 lysine 9 dimethylation mark is present (Figure 5).
This mark is present as a lawn across intergenic regions and inactive genes.
We also previously showed that this mark is present throughout the human rDNA repeat in hESCs (Zentner et al. 2011a).
However, the precise extent to which this mark is present on the Xi in other mammals needs to be systematically elucidated.
Interestingly, although the H3 K4me3) mark is present in budding yeast, the yeast Chd1 chromodomains do not maintain the aromatic cage necessary for binding to this modification, and accordingly deletion of Chd1 has little effect on +1 nucleosomes in yeast.
Running the selection algorithm with the H3K4me1 mark, the average Boruta score for the control increased notably, suggesting that the mark is present in many regions along the genome (Additional file 1: Figure S3C).
Similar(53)
In approximately half of the trials, a mark is presented in either one of four locations in the corner of the screen, and in the other half of the trials, the mark is not presented in any of the four locations.
After removing the ligature material, ligature mark was present over the neck, seen above the level of thyroid cartilage.
Immunofluorescence stainings for H3K27me3, the polycomb repressive mark set by PRC2 member Ezh2, showed that this mark was present in all cells (Figure 2B).
Interestingly, at the RARβ2 promoter, the H3K27me3 repressive mark was present in all tumor samples and H3K9me3 was detected in four of them (Fig. 1, gray bars).
As shown in Figure 2, there was a highly significant correlation between H3K4me3 and AcH3 in three cell populations, while the H3K27me3 mark was present on a distinct pool of gene promoters.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com