Sentence examples for mark is enriched from inspiring English sources

Alternatively, if such a mark is enriched this may indicate implication in remodelling.

To do this, we needed a threshold defining whether a certain mark is enriched or not.

Dots are colored according to the strain where the epigenetic mark is enriched (black: BY, red: RM, green: YJM).

For example, the H3K36me3 histone mark is enriched at the regions of high CpG density (Hahn et al, 2011).

The monomethyled H3K27me1 mark is enriched at actively transcribed promoters whereas the trimethylated H3K27me3 mark is associated with silenced promoters.

For instance, it was observed that the repressive H3K27me3 mark is enriched at the nuclear periphery in mouse embryonic stem cells [ 38].

For example, imprinted genes have both H3K9me3 and H3K4me3 marks, with the repressive H3K9me3 being located on one parental allele and the active H3K4me3 mark being enriched on the other parental allele [30].

Interestingly, Histone H3 lysine 9 dimethylation, a silencing mark, was enriched in the human DNA mismatch repair MLH1 gene promoter following chromate exposure and this was correlated with decreased MLH1 mRNA expression [11].

Indeed, paralogs that arose in the α WGD and retained their mark are enriched for long (>18 nt) stretches of high sequence similarity (Berke et al. 2012).

A recent ChIP-chip study using a polyclonal antibody directed against yeast H2BK123ub1 also found that this mark was enriched at gene coding regions [ 8].

In contrast, p63 binding sites that are not co-localized with the H3K27ac mark were enriched for the NR2 nuclear receptor family motif that can be bound by RXR family proteins (Fig 4A), suggesting that these proteins may function as repressors at p63 binding sites in keratinocytes.