Sentence examples for mark is associated from inspiring English sources

The histone H3K36 methylation mark is associated with coding regions of actively transcribed genes, yet it plays a negative role during transcription elongation.

Conversely, the presence of the H3K27me3 mark is associated with gene repression [3].

It has been shown that LIKE HETEROCHROMATIN PROTEIN 1 (LHP1) directly interacts with FT chromatin and represses FT expression [36], [37], [38]; in addition, recent whole-genome analysis of H3K27 trimethylation in Arabidopsis has revealed that this repressive mark is associated with FT chromatin [39].

Depending on density and position, this mark is associated with gene inactivation, and the formation of heterochromatin.

The histone 3 lysine 4 trimethylation (H3K4me3) mark is associated with a permissive chromatin state, whereas H3K27me3 is suppressive.

The monomethyled H3K27me1 mark is enriched at actively transcribed promoters whereas the trimethylated H3K27me3 mark is associated with silenced promoters.

The H3K27me3 mark was associated in several systems to facultative HC defined here as genomic regions that have the opportunity to adopt an open or a compact conformation within defined temporal or spatial constraints [36].

Of note, downregulation of HER-2 by induced H3K9 methylation mark was associated with inhibition of cell proliferation and clonogenicity.

Up to 4-fold induced H3K9me2 mark was associated with up to 54 ± 2.9% downregulation of HER-2 expression (P<0.0001).

ChIP-seq enrichments for H3K27me3 showed little correspondence with signals from all other ChIP libraries (data not shown), yet this repressive mark was associated with some AML1-ETO regulated genes including CXCR4 and HCK (Additional file 7: Figure S6).

Metabolic regulation of histone marks is associated with diverse biological processes through dynamically modulating chromatin structure and functions.