But when I saw the advert it occurred to me that it, and that supercilious exclamation mark in particular, could in fact give people an excuse to express their homophobia.
This framework decision gives us a toolbox for future directives, which will ensure greater legal consistency on key issues, establishing a clear and coherent position on the CE mark in particular but also on the status of importers in the trade chain.
Their marking, in particular, was poor in the extreme, both goals stemming from rebounds after some splendid goalkeeping from Joe Hart.
The second half of the 20th century was marked in particular by the worldwide proliferation of consumer lifestyles emanating from the United States.
As consumers reduced spending and stashed more money in their bank accounts, BNP Paribas said its commercial business was marked in particular by a growth trend in deposits across all its networks.
Despite this agreement in mean marking there were notable differences between student assessors and tutor marks in particular cases.
Nevertheless, the impact of enclosures set-up and fodder cultivation appeared marked in particular for Ozone depletion (46%) and Marine Eutrophication (30%), respectively.
Current understanding of the role of DNMT3L points to the process of epigenetic regulation and imprinting – parent of origin specific epigenetic marking – in particular [21], [29], [30].
EZH1 is a paralog of EZH2 found in PRC2 complexes, HOTAIR is believed to regulate the binding of PRC2 to target sequences while MLL1 has been recently proposed to resolve bivalent chromatin marks, in particular at the Dlx2 gene during the specification of the neuronal lineage [25], [26], [28].
The inheritance of epigenetic marks, in particular DNA methylation, provides a molecular memory that ensures faithful commitment to transcriptional programs during mammalian development.
We demonstrate here that in vitro exposure to very low concentrations of DNMT inhibitors can revert AML1/ETO-mediated gene silencing with high specificity, redistributing histone marks, in particular H3K27me3, and induce growth inhibitory and pro-apoptotic effects that are greater in cells that express the oncogenic protein than in those that do not.
