Sentence examples for mark for active from inspiring English sources

Because H3K27ac is a mark for active enhancers, these results indicate that MLL4 is required for the activation of cell-type-specific enhancers during adipogenesis and myogenesis.

At the same time, H3K9me is maximally reduced and H3K4me, the epigenetic mark for active transcription, increases at this stage.

The rapid rise, and critical mass, of consumers using different social networking services — Facebook, the biggest of them all, in October noted that it had passed the 1 billion mark for active users — has had a massive knock-on effect for businesses.

Especially H3K4-trimethylation (H3K4me3), a mark for active gene promoters, has been studied.

To restrict the analysis to enhancers, we used H3K27ac as a mark for active enhancers [ 33].

The H4 RH17,18CY mutations are adjacent to H4 K16, a residue whose acetylation serves as a mark for active chromatin (Millar et al., 2004).

Recruitment of PHF8 leads to a reduction of the H3K9me2-repressive mark and an increase in the H3K4me3 and H3K9Ac activation marks for active gene expression.

In hematopoietic cells, several DNase I hypersensitive sites, and in Th1 and Th2 cells the H3K4me3 chromatin mark, a sign for active transcription, were mapped within intron 10 of the Nfatc1 gene [ 48, 51].

Consistent with the increased occupancy of Cdk9, we also observed increased occupancy of H3k4Me3 (Figure 6B), and a slight increase in occupancy of H3K79Me2 (Figure 6C), both of which represent histone marks for active transcription [45].

Indeed, NM1 gene knockdown led to decreased levels of epigenetic marks for active transcription, including H3K9ac, H3K4me3 and H3K27ac, but did not affect the levels of H3K4me1.

DNase I sensitivity is an indicator of open chromatin, and DNase I hypersensitivity sites are typical marks for active regulatory regions [ 47].