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The marginal predictive ability and modest agreement between NIO assessors questions the use of resources in selection based on information from medical certificates.
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Learning that spring-training statistics do in fact have some marginal predictive power will hardly revolutionise the sport.
However, during the development of the original RISC score, RR turned out to have only marginal predictive power.
There were two datasets showing marginal predictive power for the CIN signature (GSE13507 [GEO:GSE13507] for bladder and GSE13876 [GEO:GSE13876] for ovarian cancer).
However, until now genetic variants have a marginal improvement in predictive ability above traditional risk factors for diabetes [ 2, 19].
First, the accuracy of GS is positively related to the size of the TP (e.g. [ 10, 27]) but the marginal increase in the predictive ability of a TP due to the inclusion of additional individuals decreases for large TP [ 10, 28].
It is important to establish that such specific cutoffs require demonstration of differential predictive ability and not simply demonstration of marginal distributions of the biomarker.
"We reach the point of diminishing marginal predictive returns for knowledge disconcertingly quickly," he reports.
Meanwhile, other researchers are examining factors that may further improve the predictive ability of serum tests.
"None of the other research companies have the predictive ability that we have," Mr. Cox said.
And there's still the question of the data's predictive ability.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com