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The ART criteria for marginal integrity (codes 1 and 2) consider a marginal deficiency of ≥0.5 mm to denote a failed restoration.
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This review summarizes the effects of marginal deficiencies of the essential nutrients zinc (Zn), iron (Fe), and calcium (Ca) on the enhancement of absorption and organ accumulation and retention of dietary Cd in laboratory animals.
This study determined the effects of marginal deficiencies of these essential elements on the absorption and organ retention of Cd from a natural food that contains Cd, edible sunflower kernels (Helianthus annuus L.; SFK).
Thus, it is likely that acute events in susceptible children can tip the scale of marginal deficiency to more significant deficiency; hence, the basis for WHO/UNICEF recommendations for zinc supplementation in response to an attack of diarrhea (2).
The workshop participants considered that a fundamental barrier to validation of markers able to detect marginal deficiency states was the absence of a reliable measure of zinc nutritional status.
A sensitive and reliable blood biomarker may reveal additional cases of marginal deficiency.
Whereas, a study in Addis Ababa found 0% deficiency and 11.3% marginal deficiency among lactating mothers [ 12].
There are different definitions of marginal deficiencies in the literature and we chose to use the definition from The National Veterinary Institute in Norway which defines whole blood selenium concentrations between 0.05 to 0.10 μg/g to be marginal.
Recognizing and correcting multiple vitamin marginal deficiencies may be the key to the treatment of many HIV-infected patients.
These marginal deficiencies enhanced Cd absorption as much as ten-fold from diets containing low Cd concentrations similar to that consumed by some human populations, indicating that people who are nutritionally marginal with respect to Zn, Fe, and Ca are at higher risk of Cd disease than those who are nutritionally adequate.
However, there is already sufficient evidence to suggest that marginal deficiencies in folate, vitamin B12, niacin and zinc impact significantly on spontaneous chromosome damage rate.
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