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This is where the net-benefit framework could potentially be very useful in assessing the effect of significant determinants on the marginal cost-effectiveness of a universal health coverage intervention such as the Nouna community based health insurance.
The health economic model suggests that capecitabine is expected to be more effective and less expensive than 5-FU/LV, while the marginal cost-effectiveness of FOLFOX4 versus 5-FU/LV is estimated to be below £3000 per QALY gained.
The marginal cost-effectiveness of ICDs relative to amiodarone has not been clearly established.
Measurements: Life-years gained, quality-adjusted life-years gained, costs, and marginal cost-effectiveness.
Adding an additional cytology specimen has a marginal cost-effectiveness ratio of $5,500 per reduced-quality day avoided.
A framework for quantifying uncertainty about costs, effectiveness measures, and marginal cost-effectiveness ratios in complex decision models is presented.
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In summary, the proposed critical pathway for TKA could be shown to be significantly cost efficient, but not cost effective concerning functional outcome, when the above individual marginal cost effectiveness criterion was concentrated on.
This bias may then also have been introduced into the marginal cost effectiveness estimates and thereby into the primary endpoint evaluation.
The primary health economic target parameter of the investigation was then the individual marginal cost effectiveness ratio (MCER) relating a patient's process cost sum to his/her individual gain in algo-function as assessed by means of the WOMAC index.
The health economic evaluation was based on margiual cost-effectveness ratios (MCERs); an individual marginal cost effectiveness relation ≤ 100 € per % WOMAC index increase was considered as primary endpoint of the confirmatory cohort comparison.
An individual marginal cost effectiveness relation ≤ 100 €/% WOMAC index increase was found in 38% of the patients in the pre pathway implementation cohort versus in 30% of the post pathway implementation cohort (Fisher p = 0.278).
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