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Rather, dedifferentiation of intermediate cells, altered morphology of basal and marginal cells and hearing impairment due to decreased EP in E-cadherin mutant mice demonstrate an essential role of E-cadherin in terminal basal cell differentiation and their interaction with other strial cell types to establish and maintain the functional architecture of the stria vascularis.
In superior colliculus only marginal cells and piriform neurons expressed EGFP-F (Fig. 4I J).
Thus, the effect of acoustic trauma can be similar to loop diuretics, which also increase aminoglycoside uptake by marginal cells and hair cells [40].
Time-lapse recording further showed that bleb-like cellular processes of blastoderm marginal deep marginal cells and pseudopod-/filopod-like processes of prechordal plate cells and lateral cells were abolished in the zdia2 morphants.
In contrast to the high degree of vascularization and loose association with surrounding nonvascular tissue present in other barriers, the blood-labyrinth barrier is a sandwich of epithelial marginal cells and mesodermal basal cells interconnected by TJs.
In contrast, tail bud failed to form (originally formed by fusion of the deep marginal cells) and a blastoderm ring was shown in side (Fig. 5D, open arrowheads) and vegetal pole (Fig. 5F, open arrowhead) views, along with a wider notochord (Fig. 5F) in the 8 ng zdia2 sMO-treated embryos.
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Our discovery that there are six hh-related genes expressed in arcade cells (Fig. 3H and Table 4), four in pharyngeal muscle and marginal cells (Fig. 3E and Table 3) suggests that these gene products might also be secreted to the pharynx cuticle or lumen as is WRT-5 [ 14].
In the lateral direction from the organ of Corti, the epithelium comprises spiral prominence cells and marginal cells of the stria vascularis.
An optical section of the marginal cells was observed and the recording slit, which defined the field of the Ca2+ measurement, was restricted to this cell layer.
Counting positively transduced marginal cells (Fig 3B and C) yielded viral transduction efficiencies ranging from 75±5%5% (n = 6) to 71±8%8% (n = 6) to 61 ± 10% (n = 6) for marginal cells, respectively, located in the basal, middle, and apical turns (black bars on the right of Fig 3D).
In Drosophila, cytoplasmic sequestration of active ERK is found in the developing eye and vein and marginal cells of the wing [6] [9].
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