Consistent with recently published studies, there was only marginal induction of cell death in wtp53-expressing nonmalignant cells (<15%).
Our analyses clearly showed that leoligin causes only a marginal increase in cell death (apoptosis and necrosis) in SMCs after 48 h.
Priming of myeloma cells with TNF had no or only a marginal effect on cell death-induction by the three pharmacological inhibitors suggesting that activation of the classical NF κB pathway does not interfere with the anti-myeloma effect of these clinical and preclinical drugs.
However, we show a marginal increase in cell viability in cell death assays.
AAV-APP mutant caused neuronal accumulation of amyloid peptides, and eventually amyloid plaques at 6 months post-injection, but with only marginal hippocampal cell-death.
This finding is consistent with the presence of an area of cell death termed 'Sub AER Marginal Zone of cell death' in the mouse autopod that is not present in avians.
Cell death was shown to have marginal to no effect on EMT in JLO-1 cells (Additional File 1).
In the same experimental conditions, complete glutamine depletion, cell death of K-ras transformed cells die is marginal compared to that observed in myc-overexpressing cells (data not shown).
EVOO polyphenols differentially induced breast cancer cell growth inhibition by promoting apoptotic cell death in HER2-positive breast cancer cells, with marginal tumoricidal effects occurring in HER2-negative breast cancer cells.
