Ai Feedback
Exact(6)
To correlate our in vitro findings with a relevant in vivo model, we performed a marginal bone marrow transplantation.
Our studies here show that exogenously applied CO promoted engraftment and radioprotection in a marginal bone marrow transplant model.
Exposure of mice to CO in a model of marginal bone marrow transplantation significantly improved donor myeloid cell engraftment efficiency, expansion and differentiation, which corresponded to increased serum levels of GM-CSF, IL-1 α and MCP-1.
Treatment of mice with CO for 1 h prior to marginal bone marrow transplant and then daily thereafter for 1 h resulted in 95 100% survival with increased early bone marrow engraftment versus controls.
Bone marrow marginal transplant: Mice were treated with CO for 1 h prior to irradiation with 10 Gy, and 2.5 × 10 total bone marrow cells were transplanted (suboptimal marginal bone marrow transplant) by i.v. tail injection to the irradiated recipients as previously described.
Using a model of marginal bone marrow transplant, which leads to tissue damage, we find that HO-1-derived and exogenously delivered CO modulates in part the fate of myeloid progenitors and mediates the ability of these cells to differentiate into functional mature cells.
Similar(54)
It is thought that neutrophils are mobilized from the marginal pools, including the bone marrow [26].
Our group had used the term primary bone marrow marginal zone lymphoma in order to describe those cases.
Further, although GMA carriers adsorb a large fraction of ganulocytes and monocytes from the blood which passes through the Adacolumn, but the levels of these cells in the peripheral circulation were found not to fall significantly [ 14] due to an influx of naive leucocytes (CD10 negative neutrophils) from the marginal pools including the bone marrow into the circulation [ 14].
The term MZ-CBL can better describe non-CLL-like cases with clonal B-cell lymphocytosis, irrespective of the absolute number of clonal B cells, and it may be regarded as a provisional entity, probably under the name of "primary bone marrow marginal zone lymphoma".
In 2010 our group described an entity presenting with bone marrow infiltration and blood involvement by CD5 lymphocytes of marginal zone origin without any other disease localization, which was named primary bone marrow MZL (PBMMZL) [ 61].
Related(18)
poor bone marrow
minor bone marrow
small bone marrow
incidental bone marrow
secondary bone marrow
minimal bone marrow
peripheral bone marrow
few bone marrow
marginal bone vascularity
marginal bone stability
marginal bone preservation
marginal bone remodelling
marginal bone response
marginal bone defect
marginal bone level
marginal bone height
marginal bone resorption
marginal bone loss
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com