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Exact(6)
After evaluation of the new data G-BA concluded there was a marginal additional benefit.
For rilpivirine monotherapy, IQWiG suggested a major additional benefit, whereas G-BA concluded a marginal additional benefit.
Institute for Quality and Efficiency in Health Care suggested no additional benefit, whereas G-BA concluded a marginal additional benefit.
Whereas IQWiG uses a threshold concept to define the impact that leads to a major, significant or marginal additional benefit [ 16], G-BA did not use this concept for its decisions.
However, G-BA did not agree with IQWiG regarding the additional efficacy benefit and decided for a significant additional benefit in terms of efficacy and a total score of marginal additional benefit.
Institute for Quality and Efficiency in Health Care concluded there was no additional benefit in both patient populations, whereas G-BA concluded there was a marginal additional benefit in patients that cannot be re-exposed to anthracycline and/or taxane treatment and less benefit in patients that can be re-exposed to those treatments.
Similar(54)
IQWiG concluded that there were significant and marginal additional benefits in six and three EBAs, respectively, and a non-quantifiable additional benefit was concluded in two assessments.
Incorporating them into decision making has become more important in recent years as new drugs enter the market, showing no or only marginal additional benefits [ 3].
Positive (category 1 4: major; significant; marginal; not quantifiable additional benefit) and negative (category 5 6: no/less additional benefit) decisions were discriminated.
In Economics, the ratio of Marginal Cost (MC) and Marginal Benefits (MB) measure additional benefits of every additional costs of investment at a specific level of production and consumption; and Economists suggests that effective gain and loss should be compared to the status quo, i.e., Relative Position (RP).
Combining this method with either antimicrobial stewardship or prescription of probiotics/bacteriotherapy yielded little additional benefit compared with transmission reduction alone (with marginal improvement attained by combination with antimicrobial stewardship).
Related(20)
slight additional benefit
small additional benefit
minor additional benefit
minimal additional benefit
modest additional benefit
marginal additional affinity
marginal additional design
marginal additional recovery
marginal additional stress
marginal additional file
marginal additional variance
marginal additional income
marginal additional health
marginal additional dependence
marginal additional effect
marginal additional toxicity
marginal additional investment
marginal additional impact
marginal additional value
marginal additional cost
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