Sentence examples for margin of exposure from inspiring English sources
The health risks were also evaluated using a margin of exposure based on the NOAEL from silver nanoparticle toxicity data.
A margin of exposure (MOE) approach was used to estimate the risk, where the calculated MOE was compared to a target MOE.
The margin of exposure (or MOE) of a NM is the ratio of its no-observed-adverse-effect level (NOAEL) to its predicted dose.
The margin of exposure used in this study to estimate the exposure risk is commonly used by the US EPA to analyze the exposure risk for human health.
We define the margin of exposure as the hazard quotient (HQ), quantified by dividing the exposure potential of NMs concentration in air by the threshold value OEL.
The U.S. EPA (2002) used a "margin-of-exposure" approach to assess the health risks of exposure to DLCs.
Thus, accepting the previous guideline value of 0.08 ppm (0.1 mg m−3) set by the WHO (2000), this introduces an additional margin-of-exposure.
A key element of our conclusion (Petito Boyce et al. 2008) regarding the lack of carcinogenic risk was the use of a margin-of-exposure model for iAs, which was applied using an epidemiologically derived no observable adverse effect level.
Exposure limits for carcinogens that are genotoxic or without an established nongenotoxic MOA are usually based on other approaches, in particular the linear extrapolation approach (EFSA 2005; U.S. EPA 2005), although more recently the margin-of-exposure approach has been suggested even for genotoxic carcinogens (Barlow et al. 2006; Benford et al. 2010; O'Brien et al. 2006).
Risk assessment followed the method used by the European Food Safety Authority (EFSA) to evaluate the risk of PAH contamination in food (EFSA 2008), which is based on the margin-of-exposure (MOE) approach recommended for genotoxic carcinogens in food (EFSA 2005).
