It is evident that the use of the "tangential shaved margins" technique on the BCS specimen itself [ 59] results in a significantly higher rate of "margin positivity" than what is generally seen by the more widely accepted technique of "perpendicular margins" for assessment of surgical resection margins on the BCS specimen itself.
Examples include design of TV studies, design and data 'pruning' of PKPD studies in LO, analysis of data with marginal and substantial temporal (time) differences between exposure and response, design of safety pharmacology studies, assessment of safety margin and assessment of uncertainties in predictions of first dose in human.
The purpose of this study was to compare the incidence of positive margins and rates of reexcision between two methods of margin assessment at a single institution.
In breast-conserving surgery (BCS), the method of margin assessment and the definition of a negative margin vary widely.
The Kaiser score is assigned by following a simple flowchart from the top to the bottom, which lets the reader assign the presence or absence of four diagnostic criteria (presence of spiculation being a formal subgroup of margin assessment according to BI-RADS).
The study reported here represents an initial step towards the development of an optical imaging strategy that would aid both pathologists and surgeons in expediting the process of margin assessment during surgery.
In colorectal cancer, the ability to detect and stage cancers intra-operatively has the potential to improve patient outcomes by accurate determination of resection margins and assessment of disease dissemination.
To evaluate the potential use of fluorescence confocal microscopy (FCM) for ex vivo diagnosis and excision margin assessment of conjunctival neoplasms.
This part of the review presents the methods of assessment of mesorectum quality, circumferential resection margin (CRM), distal resection margin, and lymph nodes.
But Mr. Yanukovich's margin of victory and the monitors' assessment may make it difficult for her to convince the public that her campaign was the victim of fraud.
The granulation tissue formed on the injury was excised leaving a 5 mm margin of normal skin for histopathological assessment and determination of hydroyproline.
