Sentence examples for margin considerations from inspiring English sources

Safety margin considerations.

In the safety margin considerations below, a factor of 100 instead of 81 is considered between MABEL, taken as sub-therapeutic level, and therapeutic level.

Following publication of the original article in Clinical and Translational Medicine [1], it was brought to our attention that there is an error in the section "Safety margin considerations".

The second sentence of the first paragraph of the section "Safety margin considerations" currently reads: "For first-in-human studies applying a range of escalating doses, the FDA suggests a default safety factor of ten between the exposure for the starting dose and that of the Human Equivalent Dose, which should be individualized [27]".

If the clinical significance of MRI is assessed in terms of resection margin status, consideration must be given to both the extent of EPE and the surgical plane of dissection (preserving function versus ensuring free margin).

However, these systems do not take item-specific profit margins into consideration.

A brief review of the seabed physiography and strata architecture of the margins under consideration is followed by comparison of the most relevant similarities and differences.

A two-stage evolution of the shelf prograding wedges is observed on all margins under consideration, which may reflect a general development of an ice cover from an initial phase of non- to restricted glaciation, evolving to a mature stage of expansive glaciation.

Today, we take nuclear grade, size, necrosis and margins into consideration when designing adjuvant treatment after BCS of DCIS according to the Swedish National Guidelines from the Swedish Breast Cancer Group [ 35].

This margin is informed by considerations of clinically relevance, with any treatment differences falling outside this range indicating that any dissimilarity between treatments is unacceptably large [ 9].

One additional consideration is margin compression.