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Voltage stability margin calculation without requiring the load flow solution at the bifurcation point is proposed.
The gross margin calculation, farmers are used to, is not suitable to cover the different timing of payments and revenues in a perennial system like SRC.
This may impact the numerator in the margin calculation.
Clearly, a margin calculation is dependent on a numerator, the hERG potency, and a denominator, the unbound plasma concentration.
A clinically significant difference in clinical improvement due to AV biofeedback has been determined to be a margin calculation of less than 5 mm.
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Historically, products have been launched through stage-gate product development, in which ROI and margin calculations have been the guide rails for decisions.
When running through what-if pricing scenarios, it is this handle on cost drivers that informs the ever-important margin calculations.
Margin calculations use the estimated female exposure, here Cmax, and the relevant plasma concentration corresponding to the MABEL.
Margin calculations using MABEL refer to the distinction between teratogenicity at therapeutic and sub-therapeutic levels as made in the CTFG paper.
Preclinical reference parameters In this scenario the preclinical pharmacokinetic reference parameter taken for safety margin calculations is the Area Under the Curve (AUC) associated with the NOAEL from the more sensitive animal species.
It is also important to note that no delineation uncertainty was considered in the margin calculations.
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CEO of Professional Science Editing for Scientists @ prosciediting.com